CA 125

The CA 125 Test at Pamel Laboratories measures the level of Cancer Antigen 125 (CA 125) in the blood — a protein that is often elevated in ovarian cancer and other gynecological conditions. This tumor marker is primarily used to monitor treatment response, detect cancer recurrence, and assist in the diagnosis of pelvic masses in women.

Although CA 125 can be elevated in several non-cancerous conditions, it is a key tool in evaluating women at high risk for ovarian cancer or with symptoms like abdominal swelling, pelvic pain, or unexplained weight loss.

What the Test Measures:

• The blood level of CA 125 protein, which may rise in the presence of ovarian tumors

• Used as a tumor marker in cancer screening and monitoring

Purpose of the Test:

• Monitor and manage:

  • Ovarian cancer (especially epithelial type)

  • Cancer treatment response

  • Recurrence after surgery or chemotherapy

• Assist in the diagnosis of:

  • Endometriosis

  • Pelvic inflammatory disease (PID)

  • Uterine fibroids

  • Liver cirrhosis

  • Certain other cancers (e.g., endometrial, peritoneal, and fallopian tube cancer)

Sample Type: Blood sample (serum)
Fasting Required: No
Turnaround Time: 1–2 working days

Interpretation Guide:

• Normal range: <35 U/mL

• Elevated CA 125: May suggest ovarian cancer, but also rises in benign gynecological and liver conditions

CA 125 is not a standalone diagnostic test; it must be interpreted alongside imaging studies (e.g., ultrasound, CT) and clinical evaluation