Estradiol (E2) Test

The Estradiol (E2) Test at Pamel Laboratories measures the level of estradiol, the primary and most active form of estrogen in the body. Estradiol plays a key role in the development and regulation of the female reproductive system, menstrual cycle, and secondary sexual characteristics. This test is essential for evaluating fertility issues, menstrual irregularities, menopausal symptoms, and hormonal imbalances.

In men, estradiol is present in lower amounts and helps regulate libido, bone health, and sperm production.

What the Test Measures:

• The amount of estradiol (E2) in the blood

• Reflects ovarian function in females and hormonal status in both sexes

Purpose of the Test:

• Assess and monitor:

  • Menstrual and ovulation irregularities

  • Female fertility and ovarian reserve

  • Hormone replacement therapy (HRT)

  • Menopause or early menopause

  • Polycystic Ovary Syndrome (PCOS)

  • Gynecomastia or hormone imbalance in males

• Detect:

  • Ovarian or adrenal tumors

  • Pituitary gland disorders

Sample Type: Blood sample (serum)
Fasting Required: No
Turnaround Time: 1–2 working days

Interpretation Guide:

• High estradiol levels: May indicate estrogen-producing tumors, early puberty, or hormone therapy effects

• Low estradiol levels: May suggest menopause, ovarian failure, or pituitary dysfunction

Values vary depending on age, sex, and phase of the menstrual cycle