The Estriol (E3) Test at Pamel Laboratories measures the level of estriol, a form of estrogen that is primarily produced during pregnancy. Estriol is synthesized by the placenta and plays a critical role in maintaining fetal development and maternal health. Measuring estriol levels is especially useful in prenatal screening to assess the well-being of the fetus, particularly during the second trimester.
Estriol is one of the key components of the triple or quadruple screening used to detect certain chromosomal abnormalities, such as Down syndrome (trisomy 21) and neural tube defects.
What the Test Measures:
Purpose of the Test:
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Monitor fetal development and placental health
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Screen for congenital conditions during pregnancy
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Assist in high-risk pregnancy assessment
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Used in combination with AFP and hCG in maternal serum screening panels
Sample Type: Blood sample (serum)
Fasting Required: No
Best Time for Test: Usually between 15 and 22 weeks of gestation
Turnaround Time: 1–2 working days
Interpretation Guide:
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Low estriol levels: May suggest chromosomal abnormalities, fetal distress, or placental insufficiency
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Normal or high levels: Generally indicate healthy fetal development
Should be interpreted alongside other prenatal screening results
