Cerebrospinal Fluid (CSF) – Microscopy, Culture & Sensitivity (MC&S)

The Cerebrospinal Fluid (CSF) – Microscopy, Culture & Sensitivity test at Pamel Laboratories is a critical diagnostic procedure used to identify infections or abnormalities in the central nervous system (CNS). This test involves analyzing a sample of CSF — the clear fluid surrounding the brain and spinal cord — to detect bacteria, fungi, or other pathogens, and determine the most effective treatment through antibiotic sensitivity testing.

It is especially vital in diagnosing conditions such as meningitis, encephalitis, brain abscess, or neurological complications of systemic infections.

What the Test Includes:

1. Microscopy: Examines CSF for white blood cells, red blood cells, organisms, and other abnormalities

2. Culture: Grows bacteria or fungi present in the CSF

3. Identification: Determines the specific microorganism causing infection

4. Sensitivity (Antibiogram): Tests which antibiotics or antifungals the pathogen is susceptible to

Purpose of the Test:

• Diagnose bacterial, viral, or fungal meningitis

• Detect neurological infections or abscesses

• Guide targeted antibiotic or antifungal therapy

• Support diagnosis in patients with fever, neck stiffness, seizures, altered mental state, or severe headache

Sample Type: Cerebrospinal fluid collected via lumbar puncture (spinal tap) by a qualified physician

Turnaround Time:

• Microscopy: Same day

• Culture & Sensitivity: 48–72 hours

Important Note:

• This test requires strict aseptic collection in a hospital or clinical setting

• Patients must follow pre- and post-procedure care as advised by their doctor