The Crossmatching test at Pamel Laboratories is a vital pre-transfusion compatibility test performed to ensure that the recipient’s immune system will not react adversely to donor blood. This test helps prevent hemolytic transfusion reactions, which can be serious or life-threatening.
Crossmatching involves mixing a sample of the recipient’s serum with donor red blood cells to detect any incompatibility, such as agglutination (clumping) or hemolysis. This ensures that the selected blood unit is safe and compatible for transfusion.
Types of Crossmatching:
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Major Crossmatch: Recipient’s serum is tested against donor red blood cells
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Minor Crossmatch: Donor’s serum is tested against recipient red blood cells (less commonly performed due to modern screening methods)
Purpose of the Test:
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Ensure blood compatibility before transfusion
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Prevent immune reactions to donor blood
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Detect antibodies that may cause hemolysis or agglutination
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Confirm safe transfusion in patients with prior transfusions or pregnancies
Sample Type: Venous blood from both recipient and donor
Turnaround Time:
Test Method: Tube method or gel card method (depending on clinical need)
