CSF Chloride Test (Cerebrospinal Fluid Chloride)

The CSF Chloride Test at Pamel Laboratories measures the level of chloride ions in the cerebrospinal fluid (CSF) — the clear fluid surrounding the brain and spinal cord. CSF chloride levels are essential in evaluating neurological and central nervous system disorders, particularly in cases of suspected infections, meningitis, or brain inflammation.

This test is often part of a comprehensive CSF analysis and can provide important clues about brain and spinal cord health.

What the Test Measures:

• Chloride concentration in cerebrospinal fluid

• Assesses fluid balance and the presence of neurological disease or infection

Purpose of the Test:

• Aid in the diagnosis of:

  • Meningitis (bacterial, viral, or tuberculous)

  • Encephalitis

  • Cerebral edema

  • Tuberculosis of the central nervous system

• Evaluate abnormal symptoms such as:

  • Severe headache

  • Neck stiffness

  • Seizures

  • Fever with altered mental status

Sample Type: Cerebrospinal fluid (collected via lumbar puncture)

Turnaround Time: 24–48 hours

Important Notes:

• Low CSF chloride levels are often seen in tuberculous meningitis and bacterial infections

• Normal or elevated levels can help rule out certain CNS infections

• Should be interpreted along with CSF glucose, protein, and cell count for accurate diagnosis