The TPHA Test at Pamel Laboratories is a specific serological test used to detect antibodies against Treponema pallidum — the bacterium that causes syphilis. It is commonly used as a confirmatory test following an initial screening like VDRL or CDRL, providing highly specific results to confirm a current or past syphilis infection.
TPHA is an essential diagnostic tool in sexual health evaluations, antenatal screenings, and pre-surgical assessments.
What the Test Detects:
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Treponemal antibodies in the blood
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Confirms exposure to Treponema pallidum, the causative agent of syphilis
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Positive result may indicate active, past, or treated syphilis infection
Purpose of the Test:
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Confirm syphilis diagnosis after a positive VDRL/CDRL test
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Screen for latent or untreated syphilis
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Evaluate individuals with genital ulcers, rashes, or neurological symptoms
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Required in antenatal testing, pre-marital screening, and blood donor evaluation
Sample Type: Blood sample (serum)
Turnaround Time: 24–48 hours
Important Notes:
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TPHA remains positive for life after infection, even if successfully treated
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Should be interpreted alongside non-treponemal tests (e.g., VDRL) and clinical history
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May be used to distinguish true syphilis infections from false-positive VDRL results
